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Next, to assess the identified metabolites and clinical phenotypes in further detail, we analyzed their association with visual field grades, because visual field loss is one of the most important criteria for intervention

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Indeed, NF-B triggers a cascade of molecular events, some of which may be potential key targets for the treatment of inflammation, and melatonin performs part of its anti-inflammatory functions by modulating nuclear NF-B translocation 73,78,79

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