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Cystine-1,1- 13 C was converted into the corresponding N , N - tert -butyloxycarbonyl (Boc) protected form using di- tert -butyl dicarbonate

Redox signaling across cell membranes

Given the role of ATP in tissue repair, its low level in LC patients may delay the tissue repair process resulting in sustained inflammatory condition

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Thus, the administration of N-acetylcysteine, a cysteine prodrug, replenishes intracellular GSH levels and serves as a safe and well-tolerated antidote for cysteine/GSH deficiency (125)

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