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In vivo experiments indicated that it decreases ROS accumulation, inflammatory M1 macrophages, matrix degradation, and neovascularization, significantly improving IDD pathology

The condition typically develops gradually, starting as mild stiffness that resolves with warmup, then progressing to persistent pain that limits training capacity

& Kashman, Y

doi: 10.1093/oxfordjournals.epirev.a036069

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A discriminant analysis (DA) was used to determine if variables (oxidative stress indicators and OCPs concentrations) allow discriminating or separating the groups defined a priori