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average weight loss of 9 lb in 8 weeks and up to 25 lb in 12 weeks

10.2337/db13-0903 72 NunnE.JaiswalN.GavinM.UeharaK.StefkovichM.DrareniK.et al (2024)

Headache is reported by some patients and may be related to dehydration from gastrointestinal side effects or direct pharmacological effects
Semaglutide | Comparing Benefits While injectable semaglutide is authorized for a more extensive spectrum of indications compared to dulaglutide, both peptides demonstrate similar benefits in subjects with and without T2D, as per the latest phase-3 trials
However, older GLP-1 medications like dulaglutide and liraglutide still produce clinically meaningful outcomes, often with extensive real-world experience and well-characterized safety profiles

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