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Oxidative stress induces the expression of nuclear factor (NF)-B which subsequently increases the synthesis of pro-inflammatory cytokines, such as tumor necrosis factor (TNF), interleukins (IL)-1, -6, -8, etc
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Acute Otitis Media: For the treatment of acute otitis media in pediatric patients due to susceptible strains of Streptococcus pneumoniae or Haemophilus influenzae when in the judgment of the physician sulfamethoxazole and trimethoprim offers some advantage over the use of other antimicrobial agents
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