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The great variability of GSTs co-substrates is reflected in the different H-sites shapes and chemical characters found among classes
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G.MiskolciV.et al (2019)

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Another subject, male 70 years of age, developed severe cellulitis of the lower extremity requiring hospitalization 2 wks after the last dose of ARA 290 and suffered a fatal myocardial infarction

Rodent models, particularly mice and rats, are commonly employed due to their well-established biological similarities to humans
