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Without enough vitamin B12 in your system, you may experience brain fog, poor moods, trouble sleeping, and changes in appetite

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Doctors recommend B12 shots if the patient has a deficiency of this nutrient

25 Patients diagnosed with vitamin B 12 deficiency whose history and physical examination do not suggest an obvious dietary or malabsorptive etiology should be tested for pernicious anemia with anti-intrinsic factor antibodies (positive predictive value = 95%), particularly if other autoimmune disorders are present

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Weight loss often begins gradually and continues over time with consistent use