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A broader 2024 review on cartilage engineering peptides highlighted AOD 9604 as a candidate that, in preclinical models, may support cartilage matrix restoration when delivered intra-articularly in OA settings
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MedRxiv The Preprint Server for Health Services

It is often explored in studies focusing on metabolic pathways, lipid-related processes, and peptide-specific activity

These usually improved with time or if the dose was changed
