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Finally, we evaluated whether pharmacological downregulation of CPT1 affected the normalized protein concentrations of Cyt-c, 4-HNE, Ox-LDL, AGEs and the pro-inflammatory cytokines IL-6, IL-17A and TNF-

[30] did not present improvements in 20 km time trial duration after 3 g/day of l-CLT (2 g/day l-C) for 4 weeks

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However, despite the many advances in CAD treatment, the disease is invariably associated with many limitations, most significantly the comorbid conditions that complicate treatment protocols and patients quality of life