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Interestingly, this led to the suggestion that, since no targeted therapy has been developed to date for Marfan syndrome, the prevention or reversal of the SirT1 GS-ylated state may represent a new therapeutic strategy to prevent the dissection/rupture of the TAA in these subjects [55]

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Then, 10 g of each purified extract was treated with DNAse to eliminate DNA contamination, and the RNA quality and yield were verified with Bioanalyzer chips using an Agilent RNA 6000 Nano Kit according to the manufacturers instructions

[22] Apart from Zsigmondy, Theodor Svedberg, who invented ultracentrifugation, and Gustav Mie, who provided the theory for scattering and absorption by spherical particles, were also interested in the synthesis and properties of colloidal gold