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Animal experiments have demonstrated that busulfan can induce significant cytotoxic and apoptotic effects on reproductive glands (size and weight), germ cells in spermatogenic process (sperm production and maturation) (39), and epididymal sperm (40)

However, it is important to note that infertility is a complex problem with various contributing factors

It can also affect thyroid hormone medications, reducing their effectiveness

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[DOI] [PubMed] [Google Scholar] 238.Ko E.Y., Sabanegh E.S., Jr., Agarwal A

CAT, Catalase