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Butyrate, in particular, binds to receptors on astrocytes, suppresses neuroinflammation, enhances neurotrophic factor expression, and reduces seizure frequency in epileptic rats ( The immunomodulatory functions of SCFAs are particularly noteworthy

10.3390/antiox11040749 70 Jimnez-FloresL.Lpez-BrionesS.Macas-CervantesM.Ramrez-EmilianoJ.Prez-VzquezV

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Carbohyd Polym 158:5867 Zhang SY, Li WJ, Tang XS, Nie SP, Xie MY (2017b) In vivo anti-inflammatory activity of a polysaccharide from Ganoderma atrum and its effect on mannose receptor Expression, Food

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The progeny produced by these methodologies (F1) were mated over two subsequent generations without embryo manipulations and respecting each experimental group (VT, NC), producing F2 and F3 animals (Fig