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First, we used CMS4-derived organoids (from a patient with PM) in which the catalytic subunit of glutamate-cysteine ligase (GCLC) was deleted using CRISPR-CAS9 technology

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However, in those patients with a good response to DA in terms of prolactin normalization and tumor shrinkage within sellar boundaries, at least one year before pregnancy, the drug can be withdrawn and reintroduced if tumor re-growth is observed

Therefore, finding more proteins with specific and sensitive homocysteine changes in endothelial injury is of great value for the diagnosis and treatment of AS

Expression of glutamine synthetase genes during natural senescence of tomato leaves

By way of illustration, the glutamine tag, LLQG, has been engineered into different sites in the constant domain of an antibody targeting the epidermal growth factor receptor