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Triple-negative breast cancer (TNBC) cell lines were treated with curcumin, which caused the upregulation of the TET1 gene that promoted the BRCA1 promoters hypomethylation

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HEK293T cells were pre-incubated with compound 102 at increasing concentrations (15.625125 M)

Research has indicated that when iron ions are present at specific concentrations, they can inhibit the activity of Runt-related transcription factor 2 (Runx2), a critical regulator of osteoblast differentiation ( Figure 2 )

Surgical management is beyond the scope of this article