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10.1371/journal.pone.0012748 29 MeadeE

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Direct injection of DA (up to 1 mol) into the rat striatum led to the loss of dopaminergic nerve terminals and the formation of cysteinyl adducts of DA in a DA-dose-dependent manner, and this was alleviated by co-administration of glutathione (GSH) or ascorbate [36,37,38]

CHE imparted anticancer effects on HCC827 by inhibiting PKC and caspase-3 activation, which were blocked by PMA, a PKC activator, thereby proving that CHE inhibited cancer cell viability and proliferation and induced cell apoptosis through the ROS/PKC-/caspase three pathway and glycolysis (Wang et al., 2021)

2015;5:e647

Anti-inflammatory activity of superoxide dismutases comparison of enzymes from different sources in different models in rats mechanism of action