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Complement activation, detected by the presence of C4d in the lungs of the two fatal cases, suggested that antibodyF protein immune complexes led to more severe disease 28

Autosomal-recessive intellectual disability with cerebellar atrophy syndrome caused by mutation of the manganese and zinc transporter gene SLC39A8

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Inherited disorders of vitamin B12 absorption, transport, and metabolism The years following the discovery of homocysteine brought considerable developments in our understanding of the metabolic role of vitamin B12 (also known as cobalamin)

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