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For example, the administration of the insulin growth factor small-interfering RNA blocks KET antidepressant effects in the mouse learned helplessness model of depression (Grieco et al., 2016)

de Melo IS, Sabino-Silva R, Costa MA et al (2023) N-formyl-methionyl-leucyl-phenylalanine plays a neuroprotective and anticonvulsant role in status epilepticus model

In this study, we systematically elucidated the action network of ginseng in ameliorating disorders of glucolipid metabolism through multi-target synergism (Figure 5)

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By contrast, this difference in nerve distribution could also be a reflection of the unique architecture and sinusoidal vasculature of the bone marrow, as both locally released and circulating neurotransmitters may be able to distribute throughout the bone marrow more easily than in the collagen-rich peripheral adipose tissues

[DOI] [PubMed] [Google Scholar] Smith WA, Fry AC, Tschume LC, Bloomer RJ