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People with symptoms of vitamin B12 deficiency It is a good idea for anyone with the following signs and symptoms of a vitamin B12 deficiency or pernicious anemia to consult a doctor: People with gastrointestinal issues Conditions that affect the gastrointestinal tract may affect vitamin B12 release or absorption, including: pernicious anemia, which can lead to gastric atrophy, or damage to the stomach fish tapeworm infestation bowel or pancreatic cancer folic acid deficiency overgrowth of bacteria in the small intestine diabetes thyroid disease Crohns disease celiac disease chronic pancreatitis People who have undergone gastrointestinal surgery, including weight loss, may have fewer cells necessary to secrete stomach acid and intrinsic factor

However, a 2024 systematic review in the Journal of Clinical Endocrinology and Metabolism concluded that evidence for inositols benefits remains limited and inconclusive for broader populations beyond PCOS

Vitamin B12-producing bacteria colonize the large bowel, but humans do not have the ability to absorb bacterial vitamin B12 from their large intestine

3 Vitamin B12 deficiency The haematological effects of B12 deficiency are the same as for folate deficiency, and are characterised by macrocytic anaemia (with abnormally large red blood cells)

It can stay in its active form for 48 hours

They also explain the elements of the definition of vitamin B12 deficiency