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p -values of less than 0.05 were considered significant

Higher estrogen levels feed back to the pituitary gland, causing an increase in LH (luteinizing hormone) during ovulation.[ref] Thus, when levels of androgen hormones are too high and not appropriately converted to estrogen, it interferes with ovulation or the release of the egg

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Update Pending Epidemiology and Risk factors Glaucoma is a form of optic neuropathy