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"Scholar Rock Announces Positive 12-Month Top-Line Results From the TOPAZ Phase 2 Clinical Trial Evaluating Apitegromab in Patients With Type 2 and Type 3 Spinal Muscular Atrophy (SMA)"
Furthermore, increased accumulation of TCA cycle-intermediates such as citrate, succinate and malate in CD37-deficient lymphoma cells indicated that palmitate was degraded via FAO to fuel the TCA cycle via acetyl-CoA (Fig
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23 A similar hepatic enzyme, FMO1, is responsible for a portion of TMAO production
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