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65 (6 Pt 1), 286293
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54,55 Opa1 is localized in the inner mitochondrial membrane, which is responsible for the fusion of the inner membrane, and maintains the membrane structure
It is known to elicit its toxic effects by enhanced production of ROS which adversely impact all the major cellular biomolecules: lipids, proteins and DNA
JY: Writing original draft
In this work, we identify noncovalent TGR inhibitors with efficacy against schistosome infections in mice, meeting the criteria for lead progression indicated by WHO
