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Acta 1830 , 31653172 (2013)

Oxidative Stress and the Microbiota-Gut-Brain Axis

Therefore, pharmacological agents that inhibit NF-B or p38 MAPK represent a promising class of drugs for repurposing in tinnitus, particularly for prevention in high-risk scenarios or early intervention in acute cases, by broadly suppressing the inflammatory milieu that facilitates the establishment of tinnitus see in Figure 2 , and

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The reader is referred to recent reviews addressing the pathophysiology of focal and diffuse TBI including diffuse axonal injury, a common consequence of TBI (Andriessen et al., 2010