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These fundamental aspects, which are inherently preserved in dynamical downscaling performed using physically based numerical models, are not guaranteed by the design of this study

4d), stoichiometry values on target PTM peptide level were calculated for both DDA and DIA data using the plugin peptide collapse in Perseus, with grouping columns Modified sequence and EG.PTMLocalizationProbabilities, respectively

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These data indicate considerable discrepancies even between highly sophisticated LC-MS/MS methods and point out to additional not yet fully recognized pre-analytical and/or analytical problems

In recent years, an increasing number of studies have found that vitamin D not only has a good preventive effect on the occurrence of chronic diseases, but also promotes the release of anti-inflammatory cytokines at high vitamin D levels (Argano et al., 2023)

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