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In addition to drugs that prevent lipid peroxidation, agents targeting core genes involved in ferroptosis (such as NCOA4 and NRF2) have also been explored for their potential to inhibit IPF

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These findings were however, compromised by limited spontaneous beating activity (observed only in a small subsets of cardiomyocytes in 2 of 12 differentiations) and an obviously impaired sarcomerogenesis in the Grx1-roGFP2- and mito-Grx1-roGFP2-hCMs (Figure 3C, hCM wild type shown for comparison)

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