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Messe holds a pending patent for the monitoring of upper limb movements to detect stroke and holds equity in Neuralert Technologies

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10.1038/nrm.2017.129 Nat

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This enzyme catalyzes the N-methylation of nicotinamide using S-adenosyl-L-methionine (SAM) as a methyl donor, effectively creating a "metabolic drain" that depletes both NAD+ precursors and cellular methylation capacity

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