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Research indicates that people with higher glutathione levels tend to have stronger immune responses and may be less susceptible to viral and bacterial infections

However, glutathionylation was only been detected on Cys-531 and Cys-704 indicating a high degree of specificity for this redox modification that inactivates Complex I

The singlet oxygen radical then produces 8-oxo-G and 8-oxo-dG via the oxidation of guanine, which leads to C-T transition mutation (Panich et al., 2016)

[DOI] [PubMed] [Google Scholar] 227.Wu Y., Xia S., Liang Z., Chen R., Qi S

doi: 10.1038/ng.2901 47

Additionally, GSH has a protective role against xenobiotic agents once its highly reactive thiol group binds and inactivates those agents