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Genomic studies show that GHK-Cu modulates the expression of over 4,000 genes involved in tissue repair and inflammation

Fibronectin (FN)-derived peptides have also shown to facilitate osteoblast adhesion, spreading and mineralization [185]

In young adult mice on a high-fat diet, MOTS-c also activated muscle AMPK and increased GLUT4 levels, leading to better glucose uptake in muscle and prevention of fat accumulation

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Despite these limitations, interest in the compound has continued to grow, with some healthcare providers and wellness clinics offering it through compounding pharmacies under specific circumstances