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Another exciting new approach involves using gene editing (CRISPR technology) to reverse hemoglobin switching, so that hematopoietic stem cells produce red cells that express fetal hemoglobin instead of sickle hemoglobin
doi: 10.1158/0008-5472.CAN-19-1601 47 Dehghani-GhobadiZSheikh HasaniSArefianEHosseinG
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doi: 10.1016/S0891-5849(01)00507-X
