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Glutamine, an essential metabolic substrate, exhibits significantly elevated requirements in various pathological states (Vigeland et al., 2019

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The patient should contact the physician if redness or swelling develops

Due to its wide distribution in the cochlea, preferentially in the SV and the spiral ligament (Yamasoba et al., 1998), therapeutic strategies aimed at increasing glutathione levels have been used as a proof of principle for the treatment of NIHL in rodent models

In patients with alcohol dependence and delirium unresponsive to high doses of benzodiazepines, alcoholic pellagra should be considered, since chronic alcoholism leads to a lack of tryptophan 2,3-dioxygenase, an enzyme linked to niacin synthesis