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Among them, EF induces autophagic cell death, while chloroform can stimulate iron - dependent cell death ( Nitidine chloride (NC) is an alkaloid extracted from the dried roots of Zanthoxylum nitidum, a plant of the Rutaceae family

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Conclusion The sudden outbreak of SARS-CoV2 infection is currently associated with an ongoing progress in the knowledge of underlying pathogenic mechanisms, which is highlighting the immunophenotypic traits which characterize the infected patients more susceptible to the development of heavy lung damage caused by cytokine storm

After nebulization, the LNPs distribute in the whole lung and primarily target immune and epithelial cells