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Preparation of Ce-DAB2-stained fly tissues for EM Fly brains and spinal cords were dissected according to previously described methods

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Results: Over 40% of cases without ATP7B mutations were found to have variants in upstream regulatory regions

Mechanistic research has investigated GHK-Cu as a regulator of gene expression in dermal fibroblast research models, with broad effects observed across genes involved in extracellular matrix remodeling, copper homeostasis, antioxidant defense, and tissue signaling (Pickart & Margolina, 2018)

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