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Proteolytic digestions of Mpro revealed Cys300 as a primary target of glutathionylation, and experiments using a C300S Mpro mutant revealed that Cys300 is required for inhibition of activity upon Mpro glutathionylation

Heavy metals can cause oxidation, deplete intracellular glutathione and also inhibit antioxidative enzymes

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The most prevalent form of dementia, Alzheimers disease (AD), is a neurological disorder that causes gradual memory loss

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