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Regardless of the dosage, the urinary excretion of curcumin is very low
doi:10.1093/eurheartj/ehq386

However, they are also the most expensive and most time-consuming option

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Shen BQ, Bumbaca D, Saad O, Yue Q, Pastuskovas CV, Khojasteh SC, Tibbitts J, Kaur S, Wang B, Chu YW, LoRusso PM, Girish S (2012a) Catabolic fate and pharmacokinetic characterization of trastuzumab emtansine (T-DM1): an emphasis on preclinical and clinical catabolism

Phase 1: Introduction (weeks 1 to 4) Start below your expected long-term concentration
