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Cell culture studies In laboratory studies using 3T3-L1 adipocytes, a commonly used fat cell line, researchers found that 5-amino-1mq significantly reduced intracellular levels of 1-methylnicotinamide, confirming that it was successfully inhibiting NNMT

Work from Hei Sook Suls lab demonstrated that PNPLA2 in adipocytes was required to maintain a BAT phenotype through the regulation of PPAR, a nuclear transcription factor (140)

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Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis

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