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The absence of LIP, as documented in other chemoresistant tumors [5, 27], was due to its mono- and poly-ubiquitination, followed by lysosomal and proteasomal degradation

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A deficiency can also increase the risk of chronic health conditions like heart disease, liver problems, and kidney failure

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If you are not ready for either conversation yet, that is a fair place to start

Califano V, Costantini A, Silvestri B et al (2019) The effect of pore morphology on the catalytic performance of -glucosidase immobilized into mesoporous silica