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Verdict: Fascinating research, but far from a proven anti-aging therapy

Zhang et al., 2012a,b)

Only one patient out of 406 had normal levels of both metabolites, resulting in a sensitivity of 99.8 percent when methylmalonic acid and homocysteine levels are used for diagnosis

This injection helped straight away

They also confirmed increased cytosolic ATP/ADP ratio

Patients are typically given opioids to control pain, which can worsen constipation
