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Zonulin is a protein that increases the permeability of the intestinal barrier and is often involved in the development of autoimmune diseases, including type I diabetes

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Taken together, these data provide further understanding into the regulation of CBS and in particular into the genetic relationship between DYRK1A and CBS through the Akt/GSK3 and NF-B pathways, which should help develop more effective therapies to reduce cognitive deficits in people with DS

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[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Bliss T.V., Collingridge G.L., Morris R.G