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Description
I am not a chemist but B12 does seem to be an inherently stable molecule, not least indicated by the fact that the boxes of it have long shelf from production dates on them

Smith, A., et al

and B.R.K

It is (in general) fully plateaued with daily intake of 100 g and serum/plasma levels of 70130 or 90140 g/L (depending on the study), and the concentrations of ~5.5 mg/L (measured by ELISA) were associated with the Se sufficiency (e.g., among the USA population)

Keep it refrigerated

The choice affects how often and how much you get
