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In various cancer models, PRODH has been described as a context-dependent tumor suppressor or promoter, depending on the metabolic state and microenvironment of the cell 63

For some people, the best way to achieve this is by using an oral B12 supplement

doi: 10.1007/s12672-014-0172-3 91 YooATangCZuckerMFitzgeraldKDiNataleRGRappoldPMet al

MET inhibition elicits PGC1-dependent metabolic reprogramming in glioblastoma

doi: 10.1016/j.jocn.2020.03.005 7 TrebatickJHradenZSurovcovAKatrenkovBGushinaIWaczulkovIet al

Theranostics 10:73847400 Pieniazek A, Kopera M, Gwozdzinski L, Gwozdzinski K (2022) Indoxyl sulfate induces oxidative changes in plasma and hemolysate