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2.3.1 System Xc-/GSH/GPX4 axis The System Xc-/GSH/GPX4 pathway relies on GPX4 to clear cellular L-OOHs (Chen et al., 2021b)

Antioxidants vs

DOI: 10.1016/j.bcmd.2008.02.008 27

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Additionally, calgranulin A, a calcium-binding S100 protein that binds calcium and belongs to the S100 protein family that regulates various intracellular processes was also increased relative to healthy controls in a serum study by Hsu et al
