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261 In addition to cathepsin S, CTSB has also been implicated in promoting caspase-1-mediated pyroptosis by activating the NLRP3 inflammasome, further exacerbating pancreatic inflammation

To better improve drug utilisation, the investigators further designed and synthesised the targeted ROS-responsive nanocarrier PCC-R8-ROS@miR-134-5p inhibitor (Lan et al., 2023), which more efficiently delivered the miR-134-5p inhibitor to the alveolar epithelial cells, providing a more efficient therapeutic strategy for BPD

Researchers regularly explore this axis to better understand how growth-related signals integrate with metabolism, tissue maintenance, and cellular communication

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is A4V, while the most intensely studied is G93A

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