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The histone pellet was air dried at room temperature then resuspended in glass distilled H 2 O

RNA sequencing To analyse the role of KAT6A in gene regulation in the developing brain, E12.5 dorsal telencephalon tissue was dissected and frozen, and E16.5 cortical neurons were isolated and total RNA was extracted using an RNeasy mini kit (QIAGEN) according to the manufacturers instructions including the optional DNase I digestion step

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Exemplary case from study group 4 (no-treatment control)
Hinchcliffe M, Smith A
doi: 10.1016/j.ebiom.2020.102917
