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Free radicals are the by-products of metabolic redox reactions in the respiratory chain, microsomal cytochrome P450, and immune response system triggered by several endogenous and exogenous insults such as asphyxia, inflammation, and hyperoxia (4)

Small foci of necrosis are expected to resolve more quickly than large ones

ROS can be detailed as follows

32:e13914

The existence of such a reservoir provides a plausible mechanism for how oxidative metabolism could proceed briskly in the parenchyma without being immediately reflected in vascular oxygen measurements (Schurr, 2025)

[78] conducted a small, placebo-controlled crossover trial to evaluate whether self-titrated delta-9-THC ( 25 mg/day) would reduce tremor in MS patients, but found no beneficial effect on this symptom