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The role of the gut-mast cell axis The gut contains the highest concentration of mast cells in the body

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MiR-6881-3p contributes to diminished ovarian reserve by regulating granulosa cell apoptosis by targeting SMAD4
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229,230 In a model of barrier dysfunction induced by intestinal ischemiareperfusion injury, the expression of microRNA-21 (miR-21-5p and miR-21-3p) was increased, while that of TJ proteins, including occludin and CLDN1, was decreased

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