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The 50-50-50 rule was contradicted by a study that showed a different percentage for the population (PANHARD et al., 2012)
Nat Rev Immunol 3 , 733744 (2003)

Physiology & Behavior, 92 (4), 575-582
10.1523/JNEUROSCI.3178-06.2006 15

doi:10.3389/fpls.2014.00522 To uncover new effectors of the diverse mammalian Rab GTPases, researchers performed a large-scale GST pull-down screening using 60 Rab isoforms against lysates from five cell and tissue types

SLC7A11: the Achilles heel of tumor