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These signals prompt the release of calcium ions within muscle fibers, initiating the interaction between actin and myosin filaments that produce muscle contraction

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T., & Upadhyaya, B

Antioxid and Redox Signaling (2019) 30(8):112443

From a structural pharmacology perspective, the main antidepressant active metabolites in ZSS share structural and functional similarities with commonly used clinical antidepressants in terms of molecular skeleton, functional group distribution, and lipid solubility

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