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Description
B12 is a cofactor for the enzyme, methylmalonyl-CoA mutase, which transforms methylmalonyl-CoA into succinyl-CoA, which the body can directly use in the Krebs cycle to produce ATP

Mutations in TIMM50 compromise cell survival in OxPhos-dependent metabolic conditions

This concentration allows for precise dosing across the typical 300-500mcg range with standard insulin syringes
When these pathways reactivate after deficiency, there may be increased demand for other nutrientsparticularly folate and iron
To enhance its functionality, the fragment has been modified with a tyrosine substitution and a stabilizing disulfide bridge

Results can vary depending on individual factors such as age, lifestyle, and overall health
