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SELEX: critical factors and optimization strategies for successful aptamer selection

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One limitation is that, in a variety of cell types, Nox transcript levels at baseline do not necessarily predict stimulus-induced activation of the enzymes, and opposing functions of various enzymes have been detected under different physiological conditions
The role of imaging in targeted delivery of nanomedicine for cancer therapy

Additionally, Jeney et al (108) suggested that reduced NO levels due to SOD1, itself induced by copper deficiency, may contribute to atherosclerosis by hindering vasodilation
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