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Various cationic polymers, including polyethylenimine (PEI), polyamidoamine dendrimers (PAMAM), poly-L-lysine (PLL), poly--aminoester (PBAE), and poly-lactic-co-glycolic acid (PLGA), have been developed for this purpose (Fig
The relevance to humans is unclear, as humans have fewer thyroid C-cells than rodents
While ex vivo IR studies have demonstrated cardioprotection with p66shc deletion 62 , in vivo IR studies have yielded the opposite effect 63,64
A 2023 study in Nature explained the metabolic cost of limited CoA in motor neurons, which have an exceptionally high energy demand
doi: 10.1002/cbf.1343
