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This bispecific Ab showed enhanced anti-tumor activity, reduced risk of immunogenicity and lacked endogenous biotin interference compared to the SA-biotin system

A Japanese clinical review showed significant electrophysiological improvement in neuropathy patients treated with methylcobalamin (Tokuda et al., 2018)

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Conclusion Most people get enough vitamin B12 from their diet, but some may experience a deficiency

By injecting melanoma cells into CD38/ mice, the function of CD38 could be studied and was found to be involved in (1) resistance to cell death, (2) tumor vascularization through a reduction in CD34, (3) recruitment of CAFs and (4) metastatic properties [50]